"(Not Responding)" - What does it mean, and what do I do about it?

I get this when I try to open 'computer'(Vista)to get to my external hard drive..when my phone line and Internet is disconnected I am able to access my e/hard drive easily...strange?

i'm playing call of duty waw and after 5 minutes or so the game freezes so i hit the windows button then ctrl alt del to bring up task manager and it says that the game is not responding i've been playing this game fine from it came out in nov. i tried uninstalling. running reg cleaners and all i can think of. yes and call of duty 4 it happens with it as well. just seems to be with my games

For a few weeks now i have been getting random program not responding messages. It happens when i try to open Yahoo broadband and also sometimes when logging off my computer. Then it doesnt happen for 3-4 days at a time! I have done a registry clean with Registry Mechanic and done all my maintenance checks etc. Checked for spyware and virus which comes up clean.Usually it only happens once a session but why? Im on windows xp sp/3. I have 92% space on my hard disc.But my reg check says my memory is low at 43%. I have checked for memory leak in task manager and it all seems to be ok.

Further to my recent question on why my pc kept getting program not responding messages I have uninstalled the reg mechanic as it proved pretty useless and also a spyware program and some unused programs that have never been used. Pc starts up a lot faster and so far no more program not responding messages.Fingers crossed!

Re- Program not responding....spoke to soon. Just got the dreaded message after posting last comment.

I was using a facebook while I was do some of my profile it said not responding it was very strange for what happened

XP, IE, OE 1.5 gig ram. Matsonic MS9317E+(USB) mother board 5.5 years. Crashed about a month ago with a fatal blow. Reinstalled original windows disk and all upgrades to Service pack 3. IE 7. All operations work fine--except--when shutting down it gets the "Not Responding" progress bar, not every time but more times than not. When I click on the button that says I'll lose data it shuts down normally. Starts up normally every time. Using Comodo security suite.

I have a couple problems with ERROR messages. I have xp Home edition 512 MB X86 Processor XP Service Pk 3 (Version-5.1.2600)
I have been recieving the.." Program Not Responding" when I am trying to close a window and Its been VERY VERY slow or FREEZES while I am playing online scrabble on Pogo.com. I have KASPERSKY SOFTWARE installed,
I also recieved the error RUNNDLL message, and I was told it might be related to Registry. How to I find a free registry to do all the set-ups ect??
I have the windows registry repair now and It will scan and I get a list of.. EMPTY REGISTRY, and NON-EXSISTENT FILES/FOLDERS.. The program is suppose to FIX the errors but I will get the same errors a 1 hr later.

CAN SOMEONE HELP???
Sorry for the multiple questions.. Its they drive me NUTS!!! lol
Michelle
I saved the report if I can send it to you let me know where

I am convinced that this issue is endemic to win xp or vista. It happens on my home computer and our office computers. As well. I have a number of friends who constantly complain about this issue. I have not found a suitable solution to this issue. Send your complaints to Microsoft, this is their doing.

i was using facebook while i was using facebook application it said "not responding." it was wasted my time.