Helping people with computers... one answer at a time.
In an effort to prevent malware from hijacking your browser's home page anti-spyware software may inadvertently prevent you from changing it as well.
Why, in IE's Tools, Internet Options, is the Home Page selection grayed and unusable?
Spyware. Though it's interesting that either spyware or a spyware immunization tool may in fact be responsible.
In either case, a good spyware scanner is the answer.
"Spyware" has become a term that really encompasses several types of software pests that don't quite meet the level of viruses. Several terms are routinely intermixed:
Lately, folks have been referring to all as spyware.
One common action some spyware takes is to reset your browser's home page, and keep resetting it so that you cannot. The page you are sent to is often a sales page or a pornographic web site.
A recent technique has been to also disable the user interface for changing your home page; effectively preventing you from even trying to change it back to what you would rather have it set to.
Some spyware scanners including my favorite Spybot Search & Destroy include the ability to lock the home page setting. The intent is that you can lock it before spyware tries to change it. Of course while you have it locked the Home Page selection in Tools, Internet Options, is grayed out.
So the steps are simple: first run a spyware scanner such as Spybot.
Then, check the spyware scanner immunization settings to make sure you haven't simply locked yourself out.